In the field of Chemical Biology, bioactive molecules are applied as chemical tools to probe biological processes in animals and plants. These molecules can be very useful to address fundamental research questions, but they can also be used as starting points in the development of therapeutic agents or plant-protective substances.
The identification of novel molecules requires a broad range of tools and activities including robust and innovative bio-assays, collections of screening molecules and high-throughput screening technologies. The Technology Work Group ‘Screening’ aims to assist researchers in assay development/automation and to perform high-throughput screenings of compound or siRNA collections. Each of the partners involved has its own expertise regarding the development of screening-compatible assays and screening technology. The Technology Work Group ‘Screening’ can provide the research community a broad portfolio of assays, screening libraries and high-throughput screening equipment.